Effectiveness of Probiotic Gummies in Relieving Allergic Rhinitis in Children

Exclusion Criteria

• •1. Drugs that affect the intestinal flora (including antimicrobial drugs, microecological preparations, intestinal mucosal protectors, Chinese patent medicines, etc.) have been used continuously for more than 1 week within 1 month before screening;
• •2. Patients with pulmonary tuberculosis;
• •3. Combined with allergic asthma;
• •4. Those with nasal polyps or severe nasal septum deviation;
• •5. Patients with severe systemic diseases or malignant tumors;
• •6. Those with congenital genetic diseases and congenital immunodeficiency diseases;
• •7. Those who regularly use probiotics or prebiotics within 6 months before the screening period;
• •8. Those with severe digestive tract diseases (including severe diarrhea, inflammatory bowel disease, etc.);
• •9. Patients with metabolic syndrome (including obesity, dyslipidemia, hypertension, diabetes, etc.);
• •10. Patients with sinusitis, otitis media, or respiratory tract infection;
• •11. Those who are allergic to the probiotic-related ingredients used in this trial;
• •12. Those who stop taking the test sample or add other drugs in the middle of the test, and the efficacy cannot be judged or the data is incomplete;
• •13. Those who take items with similar functions to the test in a short period of time, which affects the judgment of the results;
• •14. Subjects who are unable to participate in the test due to their own reasons;
• •15. Subjects who are judged by other investigators to be insuitable to participate.