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A Study to Compare to PK Characteristics and Safety Profiles Between AD-227 and Co-administration of AD-227A and AD-227B | Clinical Trials | Clareo Health

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A Study to Compare to PK Characteristics and Safety Profiles Between AD-227 and Co-administration of AD-227A and AD-227B

An Open-label, Randomized, Single-dose, 2-sequence, 2-period, Crossover Study to Evaluate the Safety and Pharmacokinetics of AD-227 Compared to Co-administration of AD-227A and AD-227B in Healthy Adult Volunteers Under Fasting Conditions

NCT06884085•Addpharma Inc.

View on ClinicalTrials.gov

Summary

Primary endpoint of this study is to evaluate the pharmacokinetic characteristics of AD-227 in healthy subjects.

Eligibility

Age

19 - No limit years

Sex

ALL

Healthy Volunteers

Yes

Inclusion Criteria

•Body weight equal to or greater than 50kg (Female 45kg) and Body mass index (BMI) between 18.0 kg/m2 and 30.0 kg/m2 at the time of screening visit
•The Age equal to or greater than 19 in healthy volunteers at the time of screening visit

Exclusion Criteria

•Participation in another clinical study with an investigational drug within the 6 months from scheduled first administration
•Other exclusions applied

Locations (1)

Central Hospital

Seoul, South Korea

Key Dates

Start Date

July 12, 2025

Primary Completion Date

August 13, 2025

Completion Date

August 13, 2025

Last Updated

December 1, 2025

Enrollment

ACTUAL participants

Conditions

Primary Hypertension

Interventions

Co-administration of AD-227A and AD-227B

DRUG

Administration of AD-227

DRUG

Aerobic Exercise vs Physiological Ischemic Training in Stage 2 Hypertension

NCT07375407

Primary Hypertension, Grade 2

View study

Data Source & Attribution

This clinical trial information is sourced from ClinicalTrials.gov, a service of the U.S. National Institutes of Health.

ClinicalTrials.gov last update: December 1, 2025Data synced to Clareo: March 29, 2026

Modifications: This data has been reformatted for display purposes. Eligibility criteria have been parsed into inclusion/exclusion sections. Location data has been geocoded to enable distance-based search. For the authoritative and most current information, please visit ClinicalTrials.gov.

Neither the United States Government nor Clareo Health make any warranties regarding the data. Check ClinicalTrials.gov frequently for updates.

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