Mitochondrial Function and Metabolomic Profile in Alzheimer's Disease and Related Dementias

Study will be proposed to the patient of the Nice Memory center who had a lumbar puncture and who agreed on the storage of a sample of their cerebrospinal fluid. Two groups of patients will be compared: the Alzheimer"s disease patient with positive amyloid on the cerebrospinal fluid and the non Alzheimer patient with negative amyloid on the cerebrospinal fluid. there will also be a group of healthy volonteer with one blood sample Blood samples will be collected at inclusion and one year to obtain the mitochondrial metabolomic signature