Dose-finding for Dobutamine During Transitional Circulation in Very Preterm Infants

Exclusion Criteria

• •Neonates considered non-viable, with a clinical decision not to provide life support
• •Infants with severe congenital hydrops fetalis needing chest or peritoneal drainage before recruitment
• •Infants already on dobutamine treatment
• •Infants with congenital malformations likely to affect cardiovascular adaptation (including: congenital diaphragmatic hernia, gastroschisis or congenital heart defects)
• •Infants with chromosomal anomalies
• •Lack of parental signed informed consent