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Chlorhexidine Gluconate Versus Saline for Flushing the Surgical Area During Colorectal Cancer Surgery | Clinical Trials | Clareo Health

RECRUITINGNA

Chlorhexidine Gluconate Versus Saline for Flushing the Surgical Area During Colorectal Cancer Surgery

A Comparative Study of Chlorhexidine Versus Saline Irrigation of the Surgical Area During Colorectal Cancer Surgery: a Multicenter, Stratified Randomized Controlled Trial.

NCT06869096•Nanchong Central Hospital

View on ClinicalTrials.gov

Summary

The aim of this study was to compare the effectiveness of chlorhexidine versus saline in flushing the surgical area during colorectal cancer surgery. The primary outcomes included surgical site infection, postoperative complication rates, et al.

Eligibility

Age

18 - 85 years

Sex

ALL

Healthy Volunteers

Inclusion Criteria

•1. Patients aged 18-85 years,
•2. Patients with surgically resectable colorectal tumors confirmed by CT/MRI before surgery
•3. All patients had a performance status score of 0 or 1 in the Eastern Tumor Cooperative group
•4. American Society of Anesthesiology grade I-III

Exclusion Criteria

•1. The tumor may have distant metastasis
•2. History of previous abdominal surgery
•3. The patient has a history of other malignant tumors diagnosed in the past 5 years and has received radiotherapy and chemotherapy in the past
•4. There are obvious contraindications to surgery (obvious abnormal liver and kidney function, pregnancy)
•5. Participated in other clinical trials within the past 6 months

Locations (1)

Nanchong Central Hospital

Nanchong, Sichuan, China

Key Dates

Start Date

July 2, 2024

Primary Completion Date

December 31, 2025

Completion Date

March 1, 2026

Last Updated

March 20, 2025

Enrollment

532

ESTIMATED participants

Conditions

Colorectal CancerSurgical Site InfectionChlorhexidineComplications

Interventions

Intraoperative area irrigation

PROCEDURE

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Data Source & Attribution

This clinical trial information is sourced from ClinicalTrials.gov, a service of the U.S. National Institutes of Health.

ClinicalTrials.gov last update: March 20, 2025Data synced to Clareo: March 29, 2026

Modifications: This data has been reformatted for display purposes. Eligibility criteria have been parsed into inclusion/exclusion sections. Location data has been geocoded to enable distance-based search. For the authoritative and most current information, please visit ClinicalTrials.gov.

Neither the United States Government nor Clareo Health make any warranties regarding the data. Check ClinicalTrials.gov frequently for updates.

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Chlorhexidine Gluconate Versus Saline for Flushing the Surgical Area During Colorectal Cancer Surgery

Inclusion Criteria

Exclusion Criteria

Testing the Combination of Two Anti-cancer Drugs, DS-8201a and AZD6738, for The Treatment of Advanced Solid Tumors Expressing the HER2 Protein or Gene, The DASH Trial

Clinical Trial of an Anti-cancer Drug, CA-4948 (Emavusertib), in Combination With Chemotherapy Treatment (FOLFOX Plus Bevacizumab) in Metastatic Colorectal Cancer

Study of Dato-DXd as Monotherapy and in Combination With Anti-cancer Agents in Patients With Advanced Solid Tumours (TROPION-PanTumor03)

A Study of ART0380 for the Treatment of Advanced or Metastatic Solid Tumors

Open-Label Study of BBO-10203 in Subjects With Advanced Solid Tumors

Study of RAS(ON) Inhibitors in Patients With Gastrointestinal Solid Tumors