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RECRUITINGNA

Effect of Albumin Platelet-Rich Fibrin or Leucocyte- Platelet-Rich Fibrin on Immediate Implant

Clinical and Radiographic Evaluation of Xenograft With Albumin Platelet-Rich Fibrin or Leucocyte- Platelet-Rich Fibrin on Immediate Implant Placement in Mandibular Molar Extraction Sites: Randomized Clinical Trial.

NCT06863051•Kafrelsheikh University

View on ClinicalTrials.gov

Summary

The objective of this study will be to compare between Immediate Implant grafted with xenograft and Alb-PRF gel versus xenograft with L-PRF.

Detailed Description

The objective of this study will be to compare between xenograft with Alb-PRF gel and xenograft with L-PRF ( L-PRF Block ) in the aspects of : * Peri-implant vertical defect depth. * Crestal bone level. * Bucco-lingual bone width. * Keratinized tissue width

Eligibility

Age

18 - 45 years

Sex

ALL

Healthy Volunteers

Yes

Inclusion Criteria

•* The presence of non-restorable mandibular molar.
•* Patient 18-45 years old
•* Intact buccal and lingual walls
•* Good oral hygiene.
•* Prescence of sufficient restorative space.
•* Jumping gap more than 2 mm.

Exclusion Criteria

•* Proximity of anatomical structures
•* Acute localized infection (suppuration at the surgical field)
•* Patients on chemotherapy or radiotherapy.
•* Patients who have systemic disorders (diseases) {diabetes mellitus, autoimmune disease, …etc},
•* Pregnant patients.
•* Smoking and Alcohols.
•* Presence of periapical pathology affecting the neighboring teeth.

Locations (1)

Kafrelsheikh University, Faculty of Dentistry

Kafr ash Shaykh, Kafrelsheikh, Egypt

Key Dates

Start Date

August 20, 2025

Primary Completion Date

February 10, 2026

Completion Date

February 10, 2027

Last Updated

August 1, 2025

Enrollment

ESTIMATED participants

Conditions

Immediate Implant Placement

Interventions

Immediate Implant Placement and Alb-PRF

PROCEDURE

Immediate Implant Placement and L-PRF

PROCEDURE

Contacts

Mostafa Mohamed Fayed, Demonstrator of Periodontology

CONTACT

0201004668099 mostafa.mohamed@den.kfs.edu.eg

Effect of Subepithelial Connective Tissue Graft with Socket Shield Technique

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Socket Shield Technique Implant PlacementImmediate Implant Placement

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COMPLETEDNA

Effect of "Autogenous Leukocyte Platelet Rich Fibrin- Tooth Graft" Combination Around Immediately Placed Implants

NCT04795102

Autogenous Tooth Bone GraftImmediate Implant Placement+1 more

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Data Source & Attribution

This clinical trial information is sourced from ClinicalTrials.gov, a service of the U.S. National Institutes of Health.

ClinicalTrials.gov last update: August 1, 2025Data synced to Clareo: March 29, 2026

Modifications: This data has been reformatted for display purposes. Eligibility criteria have been parsed into inclusion/exclusion sections. Location data has been geocoded to enable distance-based search. For the authoritative and most current information, please visit ClinicalTrials.gov.

Neither the United States Government nor Clareo Health make any warranties regarding the data. Check ClinicalTrials.gov frequently for updates.

View ClinicalTrials.gov Terms and Conditions

Effect of Albumin Platelet-Rich Fibrin or Leucocyte- Platelet-Rich Fibrin on Immediate Implant

Inclusion Criteria

Exclusion Criteria

Effect of Subepithelial Connective Tissue Graft with Socket Shield Technique

Effect of "Autogenous Leukocyte Platelet Rich Fibrin- Tooth Graft" Combination Around Immediately Placed Implants

The Impact of Immediate Implant Placement on Alveolar Ridge Preservation Techniques