Saves the questions and what to expect into your notes, next to the visit they belong to.
Keep this study
Lead
Amgen
Age
18–99
Sex
ALL
Healthy volunteers
Not accepted
You may be eligible if
Age ≥ 18 years.
Body mass index ≥ 30 kg/m2 or ≥27 kg/m² to \< 30 kg/m2 with at least 1 of the following weight-related comorbidities: hypertension, dyslipidemia, history of obstructive sleep apnea, history of cardiovascular disease, history of metabolic dysfunction-associated steatotic liver disease (MASLD) or Metabolic Dysfunction-Associated Steatohepatitis (MASH).
History of at least 1 self-reported unsuccessful attempt at weight loss by diet and exercise.
You may not be if
Type 1 or Typ2 diabetes mellitus.
Obesity induced by other endocrinologic disorders.
Self-reported change in body weight \> 5 kg within 90 days before screening.
Family (first-degree relative\[s\]) or personal history of medullary thyroid carcinoma (MTC) or multiple endocrine neoplasia syndrome type 2.
History of chronic pancreatitis or history of acute pancreatitis within 180 days before screening.
History of unstable major depressive disorder (MDD) or other severe psychiatric disorder within 2 years before screening.
