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The Effects of Transcutaneous Laser Therapy in Chronic Kidney Disease
Chronic kidney disease (CKD) affects approximately 10% of the global population, totaling over 800 million people. In Taiwan, one in eight individuals is diagnosed with CKD. According to National Health Insurance data, acute kidney injury and CKD rank first in medical expenditures, imposing a significant burden on patients' quality of life and the national healthcare system. Early intervention in CKD, especially for high-risk populations (e.g., individuals with diabetes or early-stage kidney dysfunction), can slow disease progression, delay the onset of kidney failure, and postpone the need for dialysis. Transcutaneous venous laser therapy is a non-invasive treatment. Current literature has demonstrated that it enhances blood circulation, alters blood and erythrocyte activity, and exhibits immunomodulatory, anti-inflammatory, and vasodilatory effects on the blood. Additionally, it boosts mitochondrial activity, which is crucial as mitochondria act as the energy powerhouses of cells, providing the necessary energy for kidneys to maintain normal function. This project aims to investigate whether this non-invasive transcutaneous venous laser therapy can reduce inflammation, improve physical activity, and further enhance patients' quality of life. It also seeks to reduce patients' medical expenses and National Health Insurance costs.
Age
20 - No limit years
Sex
ALL
Healthy Volunteers
No
Start Date
March 17, 2025
Primary Completion Date
December 31, 2025
Completion Date
January 31, 2026
Last Updated
March 18, 2025
120
ESTIMATED participants
Laser
DEVICE
Red Light
DEVICE
Lead Sponsor
National Cheng-Kung University Hospital
NCT05732727
NCT06694558
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