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Exploring the Mechanism of Osteopathic Manual Therapy (OMT) on Brain Structure and Function in Primary Headache Patients: A Pilot Study
Chronic headaches are associated with changes in brain structure and function that may be associated with increased suffering and disability. Understanding how Osteopathic Manipulative Therapy (OMT) affects these changes would reveal new insight into how the brain processes pain and returns to normal function. Also, demonstrating these changes would provide evidence regarding how OMT causes a reduction in pain and disability, supporting the recommendation for OMT as a primary treatment option for headaches.
Age
18 - 60 years
Sex
ALL
Healthy Volunteers
Yes
Auburn University MRI Center and Edward Via College of Medicine
Auburn, Alabama, United States
Start Date
August 5, 2025
Primary Completion Date
October 1, 2025
Completion Date
January 1, 2026
Last Updated
March 11, 2026
31
ACTUAL participants
Osteopathic Manipulative Therapy
OTHER
Lead Sponsor
Edward Via Virginia College of Osteopathic Medicine
Collaborators
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