Saves the questions and what to expect into your notes, next to the visit they belong to.
Keep this study
Lead
Zagazig University
Age
18–any
Sex
ALL
Healthy volunteers
Not accepted
You may be eligible if
Active acute upper gastrointestinal bleeding suspected of being of variceal origin (e.g., melena and/or hematemesis within 24 hours before inclusion) and required admission to the ICU.
Endoscopic confirmation of variceal bleeding, carried out within twelve to twenty-four hours of ICU admission, was defined by either direct visualization of blood from a gastric or esophageal varix or the presence of red color signs on varices along with blood in the stomach or esophagus, with no other identifiable bleeding source.
Cirrhosis has been confirmed through histology or by clear clinical, endoscopic, or sonographic signs of portal hypertension and cirrhosis.
You may not be if
Known hypersensitivity to Vit-K1.
Known hypercoagulopathy.
Recent history (within 6 months) including deep vein thrombosis or pulmonary embolism.
History of persistent or unstable angina pectoris, portal vein thrombosis, intermittent claudication, myocardial infarction, ischemic stroke, transient ischemic attack.
Prior parenteral or oral Vit-K1 administration within the previous two weeks.
Clareo Health | Efficacy and Safety of Intravenous Vitamin K1 in Management of Acute Variceal Bleeding
