An Open-Label Pilot Study of VTX2735 in Recurrent Pericarditis

Inclusion Criteria

• •Participants are male or female ≥ 18 years up to ≤ 75 years of age.
• •Capable of giving signed informed consent and able to comply with the protocol
• •Previously had an index (first) episode of pericarditis which met the criteria for an acute pericarditis event
• •Ongoing symptomatic episode of pericarditis, or may have an episode of recurrent pericarditis in the next 4 weeks.
• •CRP by local laboratory assessment prior to first dose of study treatment (participants with CRP ≤ 10 mg/L must be receiving corticosteroid treatment for RP and have evidence of pericardial inflammation)
• •Pericarditis pain score ≥ 4 based on the 11-point NRS.
• •Stable doses of NSAIDs, colchicine, and/or oral corticosteroids (if receiving these treatments)