Lead Sponsor

Mayo Clinic

Age

18 - No limit years

Sex

ALL

Healthy Volunteers

No

•Adults aged \> 18 years (All women of childbearing potential undergo pregnancy testing prior to THA as per our institutional protocol)
•Written informed consent
•Patients undergoing primary THA diagnosis of end-stage osteoarthritis
•Patients receiving spinal anesthesia
•Patients being discharged on postoperative day 1

•Patients with a TXA allergy
•Patients undergoing revision procedures
•Patients undergoing primary THA for a diagnosis other than end-stage osteoarthritis
•Patients receiving general anesthesia
•Patients being discharged on the same day of surgery
•Cancer patients
•Patients with a history of prior VTE event
•Patients on preoperative anticoagulants other than ASA
•Pregnant patients (All women of child bearing potential undergo pregnancy testing prior to THA as per our institutional protocol)
•Female patients who are on hormonal contraception
•Patients with history of retinal vein or artery occlusion

Related studies

NCT07020312 · Anterior Cruciate Ligament Reconstruction, Total Hip Arthroplasty (THA), and more

NCT07655388 · Wound Healing Time, Total Hip Arthroplasty (THA)

NCT06626490 · Revision Total Hip Arthroplasty, Periprosthetic Fracture of Hip

NCT05828810 · Revision Total Hip Arthroplasty (RTHA), Revision Total Knee Arthroplasty

NCT07360392 · Arthroplasty, Replacement, Knee, Pain, Postoperative, and more

Postoperative Oral Tranexamic Acid in Patients Undergoing Primary Total Joint Arthroplasty