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Study on the changes in oral microbiota during orthodontic treatment in patients aged 8-18 years. Orthodontic patients treated at Stomatology Hospital of Xi'an Jiaotong University from March 2025 to March 2027 will be recruited. Prior to orthodontic treatment, routine preoperative examinations will be conducted, informed consent forms will be signed, baseline oral conditions will be recorded, and oral and psychological-related questionnaires will be completed. Patients will be informed of the need for regular oral hygiene check-ups, caries risk assessments will be performed, and plaque, saliva, and intraoral photographs will be collected. During orthodontic treatment, plaque samples will be collected every 3 months, and saliva samples will be collected every 6 months until the treatment is completed to evaluate the changes in oral microbiota throughout the orthodontic process.
Age
6 - 18 years
Sex
ALL
Healthy Volunteers
Yes
Start Date
July 1, 2025
Primary Completion Date
March 1, 2027
Completion Date
September 1, 2027
Last Updated
June 4, 2025
150
ESTIMATED participants
no interventions
OTHER
None-placebo
OTHER
No Intervention: Observational Cohort
OTHER
Lead Sponsor
Xi'an Jiaotong University
NCT06199674
NCT05814991
Data Source & Attribution
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