National Center for Advancing Translational Sciences (NCATS)
National Institute of Mental Health (NIMH)
Healthy control participant cohort funded through K99MH141192 and depressed patient cohort funded through K99MH141192 and UM1TR004921.
Age
18–65
Sex
ALL
Healthy volunteers
Accepted
You may be eligible if
Adults ages 18-65 years
Current Major Depressive Disorder (MDD) diagnosis
Failed ≥1 antidepressant medication
Moderate-to-severe depression
Stable antidepressant medication dose for ≥ 6 weeks prior to enrollment
Healthy control participants are adults ages 18-65 years without current MDD symptoms, not taking antidepressant or antipsychotic medications, and without major psychiatric, neurological, substance use, medical conditions affecting brain function, or TMS/MRI contraindications.