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Single-shot Versus Slow Infusion Interscalene Block and Its Impact on Diaphragmatic Function in Patients Undergoing Shoulder Surgery, a Randomized Controlled Trial
Interscalene brachial plexus block is a commonly chosen anesthetic technique for shoulder and proximal arm surgery yet it carry several risks including phrenic nerve block. Researchers assumed that slow administration of local anesthetic would reduce incidence of phrenic nerve block
patients will be randomly allocated into one of 2 groups ( single shot group) and slow administration group . single shot will receive a 10 ml bolus of 0.5% bupivacaine the other group will receive 10 ml 0.5 % bupivacaine over 10 minutes (at a rate of 1ml/minute) using syringe pump An experienced operator who will be blinded to method of administration will conducted diaphragmatic excursion of ipsilateral hemidiaphragm using curved probe at baseline and at 10 minutes interval for 30 minutes Complete phrenic will be defined as 75% or more reduction in DE, while partial failure as 25%-50% reduction in DE
Age
18 - 65 years
Sex
ALL
Healthy Volunteers
No
Cairo University
Cairo, Giza Governorate, Egypt
Start Date
February 16, 2025
Primary Completion Date
May 19, 2025
Completion Date
May 19, 2025
Last Updated
May 22, 2025
80
ACTUAL participants
Diaphragmatic excursion evaluation
DEVICE
Lead Sponsor
Cairo University
Data Source & Attribution
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