Age

18–any

Sex

FEMALE

Healthy volunteers

Accepted

Able to understand and sign informed consent
Speaks English or Spanish language,
Requesting pregnancy termination or procedural management of fetal demise - Intrauterine pregnancy, 18 weeks 0 days and 24 weeks and 0 days gestation

History of or current thromboembolic event (deep vein thrombosis, stroke, pulmonary embolism)
History of coagulopathy
Anticoagulant use in the preceding five days
Severe renal impairment
Chorioamnionitis or sepsis
Suspected placenta accreta spectrum
Prophylactic uterotonics other than oxytocin given (or planned to be given) at the start of the D\&E
Known allergic reaction or hypersensitivity to TXA

Tranexamic Acid for Second Trimester Dilation and Evacuation and Bleeding Outcomes