Exercise and Movement to Enhance Resiliency in Cancer Patients

PRIMARY OBJECTIVES: Stage 1 (single-arm pilot of intervention) I. To assess the feasibility of recruitment of the EMPOWER intervention. II. To assess the acceptability of the Exercise and Movement to Enhance Resiliency in Cancer Patients (EMPOWER) intervention. Stage 2 (pilot randomized study comparing EMPOWER to enhanced usual care (EUS). I. To assess the feasibility of recruitment of the study when randomized. II. To assess the acceptability of a randomized study (in both groups) SECONDARY OBJECTIVES: Stage 1 and 2 I. To evaluate retention and adherence of the interventions. II. To evaluate the components of acceptability and adherence of the interventions. III. To evaluate changes in objective physical activity measures as a single arm pilot study (stage 1) and compared to EUS (stage 2) of the EMPOWER intervention. IV. To evaluate changes in improving patient reported quality of life measures as a single arm pilot study (stage 1) and compared to EUS (stage 2) of the EMPOWER intervention. OUTLINE: Participants will be enrolled in 2 stages. Stage 1 is a single-arm pilot study testing the EMPOWER intervention to gather feedback for refinement and optimization of the program to implement in Stage 2. Stage 2 is a pilot, randomized trial where participants will be assigned in a 1 to 1 ratio to either the EMPOWER program or EUS. All participants will be stratified by treatment type (neoadjuvant versus adjuvant therapy). Participants will be enrolled in these interventions for a total of 16 weeks and receive a 3-month follow-up.