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A Phase 1, Single-center, Open-label, Non-randomized, Fixed-sequence, Drug-drug Interaction Study to Assess the Effect of Repeated Doses of Intravenous Ceftobiprole on the Pharmacokinetics of Oral Pitavastatin (OATP1B Substrate) and on Plasma Levels of Coproporphyrin I (OATP1B Biomarker) in Healthy Subjects
Conditions
Interventions
pitavastatin
pitavastatin single dose combined with ceftobiprole
Locations
1
Netherlands
ICON Early Clinical & Bioanalytical Solutions
Groningen, Netherlands
Start Date
January 17, 2025
Primary Completion Date
February 25, 2025
Completion Date
February 25, 2025
Last Updated
April 21, 2026
Lead Sponsor
Basilea Pharmaceutica
Collaborators
Data Source & Attribution
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