Trial of JMKX003142 in Participants With Rapidly Progressive Autosomal Dominant Polycystic Kidney Disease (ADPKD)

Exclusion Criteria

• •12 weeks prior to screening, patients had taken tolvaptan or another ADPKD improvers, or patients who were assessed by the investigator to be likely to use diuretic during the trial period;
• •Praticipants who are unable to feel thirst, or have difficulty with fluid/food intake;
• •Patients who have previously received decompression surgery for renal cysts; or who received major surgery within 12 weeks before signing the ICF;
• •The investigator think that the praticipant is unable to comply with the requirements of the trial or cannot be evaluated by the trial.