Saves the questions and what to expect into your notes, next to the visit they belong to.
Keep this study
Lead
University of California, Irvine
This study is 8-weeks in duration. There are two arms in the experiment: the first is nortriptyline (7.5 mg) plus topiramate (10 mg), the second is verapamil (240 mg) plus paroxetine (32 mg). This is a double-blinded trial. Participants will be randomized to one arm for the duration of the trial using simple randomization with a computer-generated number. Both groups may receive dosage increases weekly if symptoms do not improve. Symptomatic survey scores from each arm will be obtained before and after treatment and weekly. An unblinded clinical researcher will also become involved with patients\' treatments as they start to report changes in symptoms in order to monitor their safety and provide advice on change in dosage if patients have questions.
Age
25–85
Sex
ALL
Healthy volunteers
Not accepted
You may be eligible if
Patients with mild to moderate tinnitus.
Male or female between the ages of 25 to 85 years.
Subjects must be compliant with the medication and attend study visits.
Must be able to read and write in the English language to provide consent.
You may not be if
Pregnancy will result in automatic exclusion from the study. Rule out of pregnancy will be done by urine pregnancy test to confirm the situation for all women who are of childbearing potential.
Subjects with a history of an adverse reaction to medication being prescribed.
Subjects suffering from a medical condition or have a history that may be concerning to the investigator's clinical opinion.
