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Loop Resection or Cold-cup Biopsy? A Prospective Randomized Study Evaluating the Accuracy of Detrusor Muscle Representation During Transurethral Resection of Bladder Tumors
In this report the investigators compared two deep muscle sampling methods (Loop resection and Cold-Cup Biopsy) during endoscopic resection of bladder tumors for patients with suspected bladder cancer in Tygerberg hospital. The investigators found that both sampling methods are equal effective with regards to muscle representation, regardless of surgeon experience. An important finding is that Loop Resection produced less tissue artefacts in the deep muscle specimen for the more experienced surgeons, while there was no difference for less experienced surgeons. The investigators thus conclude that - from a practical point of view - Loop Resection should be the deep muscle sampling method of choice.
Age
All ages
Sex
ALL
Healthy Volunteers
No
Stellenbosch University - Faculty of Health Sciences - Department of Urology
Cape Town, Western Cape, South Africa
Start Date
July 14, 2022
Primary Completion Date
May 23, 2024
Completion Date
July 1, 2024
Last Updated
January 28, 2025
120
ACTUAL participants
Loop Resection or Cold-cup biopsy
PROCEDURE
Lead Sponsor
University of Stellenbosch
NCT03375307
NCT07061964
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