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Effects of Vaginal or Transdermal Testosterone on Sexual Response and Climacteric Symptoms in Postmenopausal Women
The aim of the study is to elucidate the role of testosterone treatment in postmenopausal women's sexual function and their therapeutic safety.
-General To evaluate the therapeutic efficacy of testosterone treatment in sexual dysfunction in postmenopausal patients. -Specifics 1. To evaluate the prevalence of different sexual dysfunctions in postmenopausal patients, classifying them according to Diagnostic and Statistical Manual of Mental Disorders 5th (2013): * Female sexual desire / arousal disorder; * Female orgasm disorder; * pelvic or genital pain / penetration disorder; 2. To evaluate the response on climacteric symptoms after testosterone replacement using the Kupperman Menopausal Index;
Age
38 - 60 years
Sex
FEMALE
Healthy Volunteers
Yes
Flavia Fairbanks
São Paulo, São Paulo, Brazil
Start Date
October 1, 2020
Primary Completion Date
October 1, 2024
Completion Date
November 1, 2025
Last Updated
January 27, 2025
132
ESTIMATED participants
Transdermal testosterone
DRUG
Vaginal testosterone gel
DRUG
Placebo group
DEVICE
Lead Sponsor
University of Sao Paulo General Hospital
NCT04893226
NCT06841328
Data Source & Attribution
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Modifications: This data has been reformatted for display purposes. Eligibility criteria have been parsed into inclusion/exclusion sections. Location data has been geocoded to enable distance-based search. For the authoritative and most current information, please visit ClinicalTrials.gov.
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View ClinicalTrials.gov Terms and ConditionsNCT05351476