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Therapeutic Effect of Vitamin C Supplementation in Patients With Ovarian Aging:a Multicenter, Double-blind, Randomized Controlled Trial
The goal of this clinical trial is to learn if Vitamin C works to improve ovarian reserve in women with ovarian aging. It will also learn about the safety of Vitamin C. The main questions it aims to answer are: * Does Vitamin C supplementation improve the ovarian reserve prediction score? * What medical problems do participants have when taking Vitamin C supplementation? Researchers will compare Vitamin C to a placebo (a look-alike substance that contains no drug) to see if drug Vitamin C works to improve ovarian reserve in women with ovarian aging. Participants will: * Take Vitamin C or a placebo every day for 12 months * Visit the clinic once every 4 weeks for follow-up and drug distribution. * Return the Vitamin C box at each visit. * Report any adverse effects of treatment to the doctor. * Fill out a questionnaire at each visit. * After 6 months and 12 months of intervention, take blood test and ultrasonic examination.
Age
All ages
Sex
FEMALE
Healthy Volunteers
No
Start Date
July 2, 2025
Primary Completion Date
December 31, 2025
Completion Date
August 31, 2027
Last Updated
June 26, 2025
354
ESTIMATED participants
Vitamin C (Ascorbic Acid)
DIETARY_SUPPLEMENT
Vitamin C (Ascorbic Acid)
DIETARY_SUPPLEMENT
Placebo
OTHER
Lead Sponsor
Peking University Third Hospital
NCT04167033
NCT06145061
NCT05586737
Data Source & Attribution
This clinical trial information is sourced from ClinicalTrials.gov, a service of the U.S. National Institutes of Health.
Modifications: This data has been reformatted for display purposes. Eligibility criteria have been parsed into inclusion/exclusion sections. Location data has been geocoded to enable distance-based search. For the authoritative and most current information, please visit ClinicalTrials.gov.
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