Vaccine Responses in Patient With Multiple Myeloma and Non-Hodgkin Lymphoma After CAR-T Treatment

Inclusion Criteria

• •\* Willingness to provide written informed consent before any study-specific procedures or activities are performed
• •* Age ≥ 18 years of age, at the time of consent
• •* Documented, histologically or cytologically confirmed diagnosis of multiple myeloma (MM), diffuse large B cell lymphoma (DLBCL),follicular lymphoma (FL), mantle cell lymphoma (MCL), chronic lymphocytic leukemia (CLL), or small lymphocytic lymphoma (SLL), or primary mediastinal B cell lymphoma (PMBL). All number of prior lines of therapy are allowed
• •* History of prior vaccination against common VPD
• •* Approved by managing physician for CAR-T therapy, with preparative conditioning planned within the next 90 days
• •* Approved by managing physician for revaccination against Streptococcus pneumoniae or tetanus