Eastern Switzerland University of Applied Sciences
With
University Hospital, Zürich
Kantonsspital Winterthur KSW
Age
18–any
Sex
ALL
Healthy volunteers
Not accepted
You may be eligible if
We will include male and female with a confirmed diagnosis of COPD (post-bronchodilator forced expiratory volume in one second (FEV1) / forced vital capacity (FVC) ratio of \<0.7; a greater than 10 pack-year smoking history)
undergoing pulmonary rehabilitation
aged ≥ 18 years
stable condition \> 3 weeks (e.g. no exacerbations)
resting oxygen saturation (SpO2) ≥ 88%
exercise induced hypoxemia defined by a fall in SpO2 by ≥ 4% and/ or below 90% during a 6MWT
informed consent as documented by signature.
You may not be if
Severe daytime resting hypoxemia (SpO2 \< 88% )
long-term oxygen therapy, unstable condition requiring adaptation of pharmacologic and other treatment modalities or requirement of intensive care or relevant severe concomitant disease
inability to follow the procedures of the study, e.g. due to language problems, psychological disorders, neurological or orthopedic problems with walking disability or inability to ride a bicycle
women who are pregnant or breast feeding; enrolment in another clinical trial with active treatment.
Clareo Health | Hyperoxia During Outpatient Pulmonary Rehabilitation in Chronic Lung Disease - Does it Matter?
