ICP-332 in Subjects With Moderate to Severe Atopic Dermatitis

Inclusion Criteria

• •1. Male or female subjects between 18 and 75 years of age.
• •2. Clinical diagnosis of chronic atopic dermatitis (also known as atopic eczema) for at least 1 year
• •3. Documented recent history of inadequate response to TCS or TCI, or for whom topical treatments are otherwise medically inadvisable.
• •4. Subjects must meet the following criteria for disease activity:
• •* Eczema Area and Severity Index (EASI) score ≥ 16 ;
• •* (Body Surface Area )BSA affected by AD ≥ 10% ;
• •* (validated Investigator's Global Assessment-AD)vIGA-AD score ≥3 ;
• •* Baseline weekly average of daily Worst Pruritus NRS ≥ 4.
• •5. Women of childbearing potential (WOCBP) and Men must agree
• •5\. Women of childbearing potential (WOCBP) and Men must agree to contraception. 6. Willing and able to comply with scheduled visits, treatment plan, laboratory tests, and other study procedures.