Arianeb Mehrabi, Professor

CONTACT

Lead Sponsor

University Hospital Heidelberg

Collaborators

Age

18 - No limit years

Sex

ALL

Healthy Volunteers

No

•age equal or older than 18 years and
•capacity of consent and
•planned elective conventional laparoscopic or da Vinci-assisted major liver resection or resections near the liver hilum or the hepatic venous vasculature. Major liver resections are defined as the resection of 3 liver segments or more (right and left partial hepatectomies, extended right and left hepatectomies, liver resections of 3 or more segments). Right posterior sectionectomies and mesohepatectomies of ≥2 liver segments are considered resections in proximity to the liver hilum or hepatic venous vasculature.

•the participation in another trial with interference of intervention and outcome of this study,
•being a woman who is pregnant or breast-feeding or planning to become pregnant,
•American Society of Anesthesiologists (AS) score \>3,
•language barrier,
•any contraindication to a minimal invasive surgical approach or intolerance to pneumoperitoneum
•a patent foramen ovale (PFO) or any other structural cardiac defect that facilitates paradoxical gas embolisms,
•diagnosis of neuromuscular disease, heart failure NYHA \> class II or chronic obstructive pulmonary disease (COPD)
•being on oral anticoagulation therapy other than Aspirin 100mg daily or any other condition known to increase the risk of bleeding.