Kombucha in Overweight and Obese: Live Vs. Pasteurized Effects on Microbiota, Metabolism, and Liver Function

Exclusion Criteria

• •Volunteers will be excluded from the study if they present one or more of the following conditions:
• •1. Subjects with sensitivity to kombucha;
• •2. Consumption of kombucha, kefir, kimchi, cheese, raw vinegar, sauerkraut, kvass, and other fermented products during the study and in the 3 weeks before the study.
• •3. Use of antibiotics in the 6 months prior to the start of the study;
• •4. Use of pro/prebiotics or fibers as dietary supplements or any food/molecule that modifies intestinal transit time 6 weeks before recruitment; use of laxatives 6 weeks before recruitment;
• •5. Specific dietary regimen (e.g., vegan); specific dietary treatment (e.g., high protein);
• •6. Excessive consumption of substances and alcohol; smokers;
• •7. Diagnosis of gastrointestinal disorders, hormonal or thyroid diseases, autoimmune diseases, and/or chronic use of corticosteroids; psychiatric disease; Type 1 or 2 diabetes;
• •8. Use of proton pump inhibitors; antidiabetic drugs or insulin and statins;
• •9. Subjects with insulin sensitivity;
• •10. Pregnant or lactating women;
• •11. Subjects with tooth sensitivity
• •12. Participation in another clinical trial in the last 3 months.