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Not Yet RecruitingNANCT06752655

Postoperative Pain in Photodynamic Therapy Using Curcumin As a Photosensitizer

In endodontics, various irrigation solutions are used to achieve antibacterial efficacy within the root canal. The antibacterial effect of curcumin-containing root canal solutions, when combined with ...

Lead sponsor: Ataturk University•1 locations•View source on ClinicalTrials.gov

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Contacts

Meltem Sumbullu, DDS

CONTACT

+90 442 231 1111 meltem_endo@hotmail.com

Tuğçe Sönmez, DDS

CONTACT

+90 442 236 0942 dishek@atauni.edu.tr

Sponsors

Lead Sponsor

Ataturk University

Fifty patients were randomly assigned to two groups using a web-based program, according to the selected final irrigation procedure: curcumin-photodynamic therapy or a control group (routine root canal final irrigation with NaOCl and EDTA). The teeth will be isolated with a rubber dam, and access cavities will be created. After root canal preparation, the final irrigation procedure will be performed. Root canal treatments will then be completed, and the patients' postoperative pain levels will be recorded using follow-up forms.

Age

18 - 60 years

Sex

ALL

Healthy Volunteers

Yes

Inclusion Criteria

•healthy patients with aged between 18-60.
•Incisor, canine, and premolar teeth that had previously undergone root canal treatment
•Incisor, canine, and premolar teeth with a diagnosis of chronic apical abscess or asymptomatic apical periodontitis
•teeth with only 1 root canal
•the patients had not used any antibiotics for 3 months before treatment

Exclusion Criteria

•the presence of a root fracture
•teeth with any swelling
•ankyloses,
•periodontal pockets deeper than 4 mm.
•teeth which a rubber dam could not be performed
•patients with allergy to ibuprofen or ciprofloxacin were also excluded.

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Data from ClinicalTrials.govLast updated on ClinicalTrials.gov: December 31, 2024Terms

Trial snapshot

StatusNOT_YET_RECRUITING

PhaseNA

Enrollment50

Start dateJan 2025

Last updatedDec 31, 2024

Condition

Periapical Diseases Postoperative Dental Pain Irrigation Solution Photodynamic Therapy (PDT)

Locations shown

Atatürk University

Erzurum, yakutiye

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Data Source & Attribution

This clinical trial information is sourced from ClinicalTrials.gov, a service of the U.S. National Institutes of Health.

ClinicalTrials.gov last update: December 31, 2024Data synced to Clareo: June 28, 2026

Modifications: This data has been reformatted for display purposes. Eligibility criteria have been parsed into inclusion/exclusion sections. Location data has been geocoded to enable distance-based search. For the authoritative and most current information, please visit ClinicalTrials.gov.

Neither the United States Government nor Clareo Health make any warranties regarding the data. Check ClinicalTrials.gov frequently for updates.

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