Trazodone on NREM Sleep Stage Ⅲ in Depressed Insomniac Co-morbid Patients

Exclusion Criteria

• •Patients with comorbidities such as schizophrenia, schizophrenia, bipolar disorder, mental retardation, pervasive developmental disorder, delirium, dementia, cognitive impairment, alcohol dependence, etc
• •Suffering from serious organic diseases, such as diabetes, thyroid disease, hypertension, cardiovascular disease, craniocerebral trauma, cerebral ischemia or hemorrhage;
• •Patients with narrow angle glaucoma;
• •History of epilepsy and febrile seizures;
• •Individuals with a history of drug use;
• •Positive for syphilis specific antibody and AIDS antibody;
• •According to risk assessment, there are currently serious suicide attempts or individuals who are overly agitated Pregnant or lactating women, or those planning to conceive in the near future;
• •Laboratory tests indicate the presence of liver and kidney function impairment in individuals;
• •There are other individuals who meet the relevant contraindications for antidepressants.