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A Study Conducted to Evaluate the Conjunctiva and Tenon's Capsule Status of Healthy Subjects and in Participants With Neovascular Age-related Macular Degeneration (nAMD)/Diabetic Macular Edema (DME) | Clinical Trials | Clareo Health

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A Study Conducted to Evaluate the Conjunctiva and Tenon's Capsule Status of Healthy Subjects and in Participants With Neovascular Age-related Macular Degeneration (nAMD)/Diabetic Macular Edema (DME)

A Multicenter, Cross-sectional Study to Describe the Conjunctiva and Tenon's Capsule Status of Healthy Subjects and nAMD/DME Patients Followed in Clinical Practice in Spain

NCT06723288•Hoffmann-La Roche

View on ClinicalTrials.gov

Summary

The purpose of this study is to obtain conjunctiva and tenon's capsule thickness measurements in vivo using spectral domain-optical coherence tomography (SD-OCT) in participants with nAMD/DME and age-matched healthy subjects.

Eligibility

Age

45 - No limit years

Sex

ALL

Healthy Volunteers

Yes

Inclusion Criteria

•For nAMD/DME participants:
•\- Diagnosis of nAMD/DME
•For healthy subjects:
•\- Normal visual function

Exclusion Criteria

•Current or past treatment for glaucoma (only for healthy subjects)
•Dry eye disease except those treated only with artificial tears
•Ocular hypertension treated with hypotensive drugs
•Pterygium
•Strabismus
•Previous ocular surgery except cataract surgery
•Cataract surgery with scleral incision
•Current contact lens wearers
•Myopia with more than 6 diopters
•Corneal transplant
+4 more criteria

Locations (20)

Hospital Universitario de Bellvitge

L'Hospitalet de Llobregat, Barcelona, Spain

Hospital General de Catalunya

San Cugat Del Valles, Barcelona, Spain

Hospital Universitario Puerta de Hierro

Majadahonda, Madrid, Spain

Clinica Universitaria de Navarra

Pamplona, Navarre, Spain

Instituto Oftalmologico Fernandez Vega

Oviedo, Principality of Asturias, Spain

Oftalvist Valencia

Burjassot, Valencia, Spain

Centro de Oftalmologia Barraquer

Barcelona, Spain

Institut de la Macula i la retina

Barcelona, Spain

Hospital Universitario Vall d Hebron

Barcelona, Spain

Hospital Clínic i Provincial de Barcelona

Barcelona, Spain

Key Dates

Start Date

December 31, 2024

Primary Completion Date

November 28, 2025

Completion Date

November 28, 2025

Last Updated

February 27, 2026

Enrollment

736

ACTUAL participants

Conditions

Neovascular Age-related Macular DegenerationDiabetic Macular Edema

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RECRUITINGPHASE3

CAPRI: A Phase 3 Randomized, Double-Masked Study Comparing the Efficacy of EYP-1901 Against Aflibercept in DME

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Data Source & Attribution

This clinical trial information is sourced from ClinicalTrials.gov, a service of the U.S. National Institutes of Health.

ClinicalTrials.gov last update: February 27, 2026Data synced to Clareo: March 29, 2026

Modifications: This data has been reformatted for display purposes. Eligibility criteria have been parsed into inclusion/exclusion sections. Location data has been geocoded to enable distance-based search. For the authoritative and most current information, please visit ClinicalTrials.gov.

Neither the United States Government nor Clareo Health make any warranties regarding the data. Check ClinicalTrials.gov frequently for updates.

View ClinicalTrials.gov Terms and Conditions

A Study Conducted to Evaluate the Conjunctiva and Tenon's Capsule Status of Healthy Subjects and in Participants With Neovascular Age-related Macular Degeneration (nAMD)/Diabetic Macular Edema (DME)

Inclusion Criteria

Exclusion Criteria

COMO: A Phase 3 Randomized, Double-Masked Study Comparing the Efficacy of EYP-1901 Against Aflibercept in DME

CAPRI: A Phase 3 Randomized, Double-Masked Study Comparing the Efficacy of EYP-1901 Against Aflibercept in DME

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