LEOPARD Prospective Validation Cohort 1

Inclusion Criteria

• •Adult \[age 18;70\] patients listed for:
• •* decompensated cirrhosis as primary diagnosis, irrespective of liver disease etiology (subset1) OR
• •* other end-stage liver diseases requiring LT, listed under MELD offering schemes (subset 2), including notably but not exclusively cholestatic diseases, primary biliary cholangitis, primary sclerosing cholangitis (subset 2) OR
• •* HCC as primary diagnosis, whatever the etiology of the underlying liver disease with or without underlying cirrhosis (subset 3). (HCC diagnosed on Barcelona/EASL criteria or histologically proven. HCC meeting or not Milan criteria, as per center practice.)
• •Patients registered on national waiting lists under the MELD offering schemes, regardless of extra MELD points are affected or not.
• •Patient (or trusted person, family member or close relation, if the patient is unable to express consent) who has been informed and signed the informed consent.
• •Patient affiliated with a health insurance scheme (beneficiary or entitled party).