Saves the questions and what to expect into your notes, next to the visit they belong to.
Keep this study
Lead
Novo Nordisk A/S
Age
18–55
Sex
MALE
Healthy volunteers
Not accepted
You may be eligible if
Male.
Age 18-55 years (both inclusive) at the time of signing the informed consent.
Body mass index (BMI) between 27.0 and 34.9 kilogram per meter square (kg/m\^2) (both inclusive) at screening. Overweight should be due to excess adipose tissue, as judged by the investigator.
Body weight more than or equal to (\>=) 80.0 kilograms (kg) at screening.
Considered eligible based on the medical history, physical examination, and the results of vital signs, electrocardiogram and clinical laboratory tests performed during the screening visit, as judged by the investigator.
You may not be if
Known or suspected hypersensitivity to study intervention(s) or related products.
Exposure to an investigational medicinal product within 2 months or 5 half-lives of the investigational medicinal product (if known), whichever is longer, before screening.
Participants report prior receipt of an amylin and/or calcitonin receptor agonist within the last 6 months.
Impaired liver function defined as any of the below:
Aspartate aminotransferase (AST) more than or equal to (\>=) 2 times upper limit of normal at screening
Alanine aminotransferase (ALT) more than or equal to (\>=) 2 times upper limit of normal at screening
Bilirubin more than (\>) 1.5 times upper limit of normal at screening (except if known or proven Gilbert's syndrome)
Renal impairment with estimated Glomerular Filtration Rate (eGFR) less than (\<) 75 milliliters per minute per 1.73 square meter (mL/min/1.73 m\^2) at screening.
Glycated haemoglobin (HbA1c) more than or equal to (\>=) 6.5 percent (%) (48 millimoles per mole (mmol/mol) at screening.
Any clinically significant body weight change more than or equal to (\>=) 5 percent (%) self-reported change) or dieting attempts (e.g., participation in a weight reduction program) within 90 days before screening .
Any disorder, unwillingness or inability which in the investigator's opinion, might jeopardize the participant's safety or compliance with the protocol.
Any laboratory safety parameters at screening outside the below laboratory ranges, see designated reference range documents for specific values:
Vitamin D (25-hydroxycholecalciferol) less than (\<) 12 nanogram per milliliter (ng/mL) (30 nanometer (nM) at screening
Parathyroid hormone (PTH) outside normal range at screening
Total calcium outside normal range at screening
Calcitonin more than or equal to (\>=) 50 nanogram per liter (ng/L) at screening
