Patients with Major Depressive Disorder (MDD), as defined by the DSM-5-TR criteria;
Presence of residual symptoms, defined by a Hamilton Depression Rating Scale score over 7;
Age over 18 years.
You may not be if
MMSE under 18 and/or CDR over 2;
Other neurological diseases (stroke, multiple sclerosis, major head trauma, epilepsy) or psychiatric disorders other than those included (schizophrenia, bipolar disorder, etc.);
Patients with severe clinical conditions, acute or uncontrolled chronic medical diseases;
Endocrine diseases, vitamin deficiencies, or exposure to drugs associated with cognitive impairment and/or mood deflection;
Alcohol abuse or recreational drug use;
Contraindications to MRI and TMS (carriers of implanted devices, patients who have undergone craniotomy, presence of metal fragments or prostheses, history of epilepsy);
Pregnant or breastfeeding women.
Clareo Health | Non-invasive Brain Stimulation in Subjects with Major Depressive Disorder
