for all patients detailed history taken clinical and rhumatological examination will be assessed and SLEDAI score will be collected from the case record of the patients\&laboratory investigation included 1\_erythrocytic sedimentation rate.2\_complete blood count.3\_interleukin23 .4\_complement 3\&4.5\_Antinuclear Antibodies.6\_Anti double stranded antibodies.7\_full basic biochemical test(24 urine protien)8\_high resolution computed tomography.
Age
18–60
Sex
ALL
Healthy volunteers
Accepted
You may be eligible if
patients with systemic lupus erythematous and patients with systemic lupus erythematosus with interstial lung disease.
You may not be if
patients with chest conditions rather than interstial lung disease \&who receiving biological blocking antibodies\& those treated with immunosuppressive drugs.