Evaluation of Gixam's Efficacy Predicting Pre-cancerous Colorectal Polyps and Colorectal Cancer

1. Average risk persons eligible for CRC screening that have received a positive FIT outcome in the past 6 months and are scheduled for a screening colonoscopy at one of the participating centers will be offered to participate in the study. 2. Following the informed consent process, subjects will undergo the Gixam test. 1. A subset of 50 subjects will participate in the repeatability assessment. They will undergo three (3) repetitive Gixam tests one after the other, by the same operator. 2. Both the subject and the endoscopist will be blinded to the Gixam outcome 3. All subjects will thereafter undergo a standard of care HD-WL colonoscopy procedure. 4. All resected and retrieved lesions will be sent separately for histopathological evaluation.