Early Catheter-directed Treatment of High Risk Pulmonary Embolism

Exclusion Criteria

• •1. Contraindications for catheter-based treatment
• •2. Contraindications to systemic fibrinolytic treatment or anticoagulation\*
• •1. Active, potentially life-threatening bleeding
• •2. Surgery within 24h before screening
• •3. Cranial or spinal surgery within 14d before screening
• •4. Stroke within 14d before screening
• •5. Intracranial tumor
• •6. Any condition not listed here but estimated as clinically relevant as judged by the treating investigator
• •3. Pregnancy
• •* Patients with contraindications to systemic fibrinolysis or anticoagulation can be enrolled in a third study arm (registry) and undergo catheter-directed therapy.