Effects of Real vs. Soundless Acoustic Stimulation During Deep Sleep on Brain Activity, Memory, and Blood Biomarkers in Older Adults (60-85) With Mild Memory Impairment

Exclusion Criteria

• •Insomnia assessed by the Regensburg Insomnia Scale (RIS; Crönlein et al., 2013)
• •Restless leg syndrome assessed by questions concerning typical symptoms.
• •Sleep apnoea assessed by the Berlin Questionnaire (BQ; Netzer et al., 1999)
• •Severely irregular sleep patterns assessed by the RIS and the Pittsburgh sleep quality index (PSQI; Buysse et al., 1989)
• •Symptoms of depression (Geriatric Depression Scale (GDS; Yesavage et al., 1982) ≥ 5)
• •History of untreated severe neurological and psychiatric diseases
• •Alcohol or substance abuse
• •Use of medication acting on the central nervous system