Saves the questions and what to expect into your notes, next to the visit they belong to.
Keep this study
Lead
University of Washington
OUTLINE: Patients are randomized to 1 of 2 arms.
ARM A: Patients receive SOC lidocaine via injection during SOC prostate biopsy on study.
ARM B: Patients receive buffered lidocaine via injection during SOC prostate biopsy on study.
After completion of study intervention, patients are followed up 1-2 days post-biopsy.
Age
18–any
Sex
MALE
Healthy volunteers
Not accepted
You may be eligible if
Provision of signed and dated informed consent form
18 years old or older
Patients with prostates
Those with and without a prior diagnosis of prostate cancer
Recommended to undergo a prostate biopsy in the urology clinic. Only patients that have been scheduled for a biopsy (for clinical purposes) will be enrolled. May include all of the following types of prostate biopsies:
* Transperineal or transrectal
* Systematic or targeted/fusion biopsy
* 12 core biopsy or \> 12cores
* Biopsy naïve or prior biopsy
You may not be if
Anorectal pathology precluding placement of a transrectal ultrasound
Diagnosis of chronic prostatitis, interstitial cystitis, pelvic pain syndrome
Prostate biopsy performed with any anesthesia other than local anesthetic (monitored anesthesia care, general anesthesia)
Prostate biopsy completed in the operating room
Patients who ultimately require additional local anesthetic beyond what is allotted in the study intervention
Patients taking anxiolytics in the 6-hours prior to the biopsy
Those with a known hypersensitivity, allergic reaction, or contraindication to using sodium bicarbonate. This includes patients who are receiving diuretics known to produce a hypochloremic alkalosis
