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Assessing the Immediate Increase in Serum Ferritin After Oral Iron Doses | Clinical Trials | Clareo Health

COMPLETEDNA

Assessing the Immediate Increase in Serum Ferritin After Oral Iron Doses

Assessing the Immediate Increase in Serum Ferritin After Oral Iron Doses: an Experimental Study in Iron-deficient Women.

NCT06657677•Jessica Rigutto

View on ClinicalTrials.gov

Summary

Serum ferritin is a key indicator of body iron stores and is widely used in monitoring iron status. However, oral iron doses can acutely elevate SF levels, potentially biasing assessments of iron stores during supplementation. This study aims to investigate the extent and duration of the acute iron-induced effect on serum ferritin, as well as its protein characteristics, following the administration of a single iron dose

Eligibility

Age

18 - 45 years

Sex

FEMALE

Healthy Volunteers

Yes

Inclusion Criteria

•Low iron stores (SF levels \< 30 µg/L),
•no anemia (Hb \> 120 g/L)
•no inflammation (CRP \< 5 mg/L)
•18 to 45 years old.
•Body weight \<70 kg
•Normal body Mass Index (18.5-26.5 kg/m2)

Exclusion Criteria

•Any chronic or acute disease
•Consumption of mineral and vitamin supplements since screening and over the study period
•Blood transfusion, blood donation or significant blood loss over the past 6 months,
•Pregnant or breastfeeding,
•Continuous/long-term use of medication during the whole studies (except for contraceptives)
•Therapeutic iron infusion over the past 6 months,
•Known hypersensitivity or allergy to iron supplements,
•Intention to become pregnant over the course of the study

Locations (2)

ETH Zurich

Zurich, Canton of Zurich, Switzerland

Laboratory of Nutrition and Metabolic Epigenetics

Zurich, Canton of Zurich, Switzerland

Key Dates

Start Date

October 25, 2024

Primary Completion Date

December 16, 2024

Completion Date

December 16, 2024

Last Updated

February 27, 2025

Enrollment

ACTUAL participants

Conditions

Iron Deficiency (Without Anemia)

Interventions

40mg oral iron dosing

DIETARY_SUPPLEMENT

100mg oral iron dosing

DIETARY_SUPPLEMENT

180mg oral iron dosing

DIETARY_SUPPLEMENT

Iron Status of Non-anemic Pregnant Women in First Trimester

NCT06990373

Iron Deficiency (Without Anemia)Reference Values+1 more

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COMPLETEDNA

Effect of Low-dose Versus Standard-dose Iron Supplementation on the Gut Microbiome

NCT05467423

Iron Deficiency (Without Anemia)

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Data Source & Attribution

This clinical trial information is sourced from ClinicalTrials.gov, a service of the U.S. National Institutes of Health.

ClinicalTrials.gov last update: February 27, 2025Data synced to Clareo: March 29, 2026

Modifications: This data has been reformatted for display purposes. Eligibility criteria have been parsed into inclusion/exclusion sections. Location data has been geocoded to enable distance-based search. For the authoritative and most current information, please visit ClinicalTrials.gov.

Neither the United States Government nor Clareo Health make any warranties regarding the data. Check ClinicalTrials.gov frequently for updates.

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Assessing the Immediate Increase in Serum Ferritin After Oral Iron Doses

Inclusion Criteria

Exclusion Criteria

Iron Status of Non-anemic Pregnant Women in First Trimester

Effect of Low-dose Versus Standard-dose Iron Supplementation on the Gut Microbiome

Improving the Iron Status of Athletes With Pre-, Pro- and Synbiotics

Effect of Ferrous iROn and cUrcumin sTatus on Inflammatory and Neurotrophic markErs