Saves the questions and what to expect into your notes, next to the visit they belong to.
Keep this study
Lead
University of Colorado, Denver
Age
18–70
Sex
ALL
Healthy volunteers
Not accepted
You may be eligible if
All participants ages 18-70 with diagnosis of multiple sclerosis at least 30 days from last relapse
Baseline grooved peg test time greater than or equal to 91 seconds for completion of the task (2 standard deviation above mean multiple sclerosis score).
Ability to sign informed consent
Expanded disability status scale score (or estimated) of 2.5 or greater OR a clinical report of upper extremity dysfunction in their dominant hand
You may not be if
Current uncontrolled and/or clinically significant medical condition.
History of seizures or epilepsy.
Other central nervous system disease or significant brain trauma.
Bacterial or viral infection within the prior 30 days.
Prior treatment with total body irradiation, clemastine, bexarotene, or other experimental remyelinating agent.
Recent suicide attempt or continued expressed suicidal ideation.
Implanted devices, such as pacemakers, cochlear prosthesis, neuro-stimulators.
Abnormal ear anatomy or ear infection.
Pregnancy, lactation, or lack of use of contraception.
Unable to walk 25 feet continuously
Other significant disease or disorder that might impair study participation. Participants will be allowed to initiate or maintain background disease modifying therapy to reduce the risk of multiple sclerosis relapse and optimize recruitment.
Clareo Health | Study to Investigate Vagus Nerve Stimulation Paired With Motor Task for Remyelination and Functional Recovery
