International Society of Urological Pathology (ISUP) grade group (GG) ≥ 3 and/or PSA ≥ 20 ng/ml and/or ≥cT3a.
If all of the criteria above are met, a subject must also meet all of the following subgroup specific criteria:
Group 1 (n=15):
\- PSMA PET/CT with PSMA-avid primary tumor with PSMA-avid loco-regional and/or distant metastases.
Group 2 (n=15):
PSMA PET/CT with PSMA-avid primary tumor with no PSMA-avid loco-regional or distant metastases;
Increased risk of nodal metastases according to the Briganti 2019 nomogram (Briganti ≥40%) \[22\];
Scheduled for (laparoscopic) prostatectomy including ePLND.
You may not be if
Known second malignant disease that may complicate image interpretation.
Inability to cooperate with the scan process: inability to lie relatively still and in supine for 30-60 minutes or patient body habitus above scanner dimensions.
Clareo Health | The Diagnostic Value of FAPI PET/CT in Staging of Newly Diagnosed Prostate Cancer
