The EPIC Study: Exploring Paternal Age and the Influence on Blastocyst Culture

Exclusion Criteria

• •Contraindication to IVF
• •Clinical indication for preimplantation genetic testing (i.e., screening for single gene disorder, chromosomal translocation, or any other disorders requiring a more detailed embryo genetic analysis)
• •Male partner with azoospermia or oligozoospermia (\<500,000 total motile spermatozoa on the most recent semen analysis within one year of enrollment)
• •Planned for previously cryopreserved sperm to be used for ICSI
• •Donor sperm
• •Male partner with Y-chromosome microdeletion
• •Male partner with any Karyotype other than 46,XY
• •Male partner requiring surgically obtained sperm either via testicular or epididymal retrieval procedures
• •Uncorrected hydrosalpinges that communicate with the endometrial cavity
• •Endometrial Insufficiency, as defined by a prior cycle with maximal endometrial thickness \<6mm,), or persistent endometrial fluid
• •Donor oocyte or embryo cycles
• •Gestational carriers