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Effect of Aerobic Exercise with Blood Flow Restriction on Post-exercise Hypotension in Young Adults: the Role of Histamine Receptors | Clinical Trials | Clareo Health

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Effect of Aerobic Exercise with Blood Flow Restriction on Post-exercise Hypotension in Young Adults: the Role of Histamine Receptors

NCT06629337•California Baptist University

View on ClinicalTrials.gov

Summary

It was hypothesized that aerobic exercise with blood flow restriction (BFR) induced post exercise hypotension (PEH), and the reduction in blood pressure (BP) was due to peripheral vasodilation via the histamine receptors. Ten male participants participated in this study. The participants were randomly assigned to walk for 10 minutes at 6.4 k/m, 0% grade with or without BFR after taking histamine receptor blockade. Following exercise, BP was measured at 10 min interval for 60 minutes. Heart rate (HR), stroke volume (SV), cardiac output (CO), mean arterial pressure (MAP), and total peripheral resistance (TPR) were evaluated.

Eligibility

Age

18 - 30 years

Sex

MALE

Healthy Volunteers

Yes

Inclusion Criteria

•good health,
•nonsmokers
•those not taking medications that could affect cardiovascular function

Exclusion Criteria

•hypertension
•muscular skeletal disorder

Locations (1)

California Baptist University

Riverside, California, United States

Key Dates

Start Date

April 1, 2024

Primary Completion Date

August 31, 2024

Completion Date

August 31, 2024

Last Updated

October 8, 2024

Enrollment

ACTUAL participants

Conditions

Prehypertension (elevated Blood Pressure) or Hypertension

Interventions

H1 receptor blockade: 540 mg (Allegra), H2 receptor blockade: 40 mg (Pepcid AC)

GENETIC

Evaluation of Physical Fitness and Hemodynamics Across a Diverse Population

NCT06669715

Prehypertension (elevated Blood Pressure) or HypertensionObesity and Obesity-related Medical Conditions

View study

Data Source & Attribution

This clinical trial information is sourced from ClinicalTrials.gov, a service of the U.S. National Institutes of Health.

ClinicalTrials.gov last update: October 8, 2024Data synced to Clareo: March 29, 2026

Modifications: This data has been reformatted for display purposes. Eligibility criteria have been parsed into inclusion/exclusion sections. Location data has been geocoded to enable distance-based search. For the authoritative and most current information, please visit ClinicalTrials.gov.

Neither the United States Government nor Clareo Health make any warranties regarding the data. Check ClinicalTrials.gov frequently for updates.

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