Treatment of Angioedema Attacks in Adolescent and Adult Patients 12 Years and Older With HAE Type I or II With Sebetralstat

Exclusion Criteria

• •Confirmed diagnosis of HAE with nC1-INH or acquired angioedema.
• •Confirmed pregnancy or breast-feeding.
• •Any clinically significant medical condition or medical history that, in the opinion of the Treating Physician, would interfere with the patient's safety.
• •Known hypersensitivity to sebetralstat or its excipients.
• •Patient with a medical history or known to have severe hepatic impairment (Child Pugh C).
• •Patients who require sustained use of strong cytochrome P450 3A4 inhibitors or inducers.