Blue Light as an Anti-inflammatory and Analgesic Strategy in Thoracic Trauma

Exclusion Criteria

• •Mechanical ventilation\* or non-invasive positive pressure ventilation administered for respiratory insufficiency prior to the time of informed consent
• •Delirium (positive CAM screening) at the time of informed consent
• •Ocular trauma, which may interfere with the mechanism of action
• •Traumatic brain injury (TBI) or history of TBI or stroke, which may interfere with the mechanism of action
• •Splenectomy upon admission or history of splenectomy, which may interfere with the mechanism of action
• •History of significant ocular dysfunction\*\* (i.e., macular degeneration, glaucoma, cataracts), which may interfere with the mechanism of action
• •History of cataract surgery, due to the possibility of blue light filtering intraocular lens placement
• •History of bipolar disorder or schizophrenia, which could increase the risk of an adverse reaction to light exposure (i.e., acute mania)
• •History of dementia, which would compromise the reliability of pain intensity and delirium measures
• •* Or other condition in which a patient cannot open eyes to receive light intervention or report a pain score \*\*Myopia, hyperopia, and/or astigmatism corrected for with contact lenses or spectacle corrective eyeglasses will NOT be a criterion for exclusion