Efficacy and Safety of Thalidomide Combined With Glutamine in the Treatment of Radiation Intestinal Injury.

Exclusion Criteria

• •Patients with hemodynamic instability;
• •Patients with obvious liver and kidney function injury: bilirubin, aminotransferase (ALT, AST) exceeded the upper limit of normal by 2 times; eGFR\<60ml/min or dialysis patients;
• •Patients allergic to thalidomide or glutamine;
• •Patients whose primary disease was gastrointestinal malignancy;
• •Patients currently suffering from serious or uncontrolled underlying diseases of the blood, digestive tract, metabolism, endocrine, lung, heart, nervous system, mental system, etc.;
• •Female patients during pregnancy and breastfeeding (including patients with reproductive needs);
• •Patients infected with HIV;
• •Patients who cannot cooperate with regular follow-up and review of laboratory indicators;
• •any other circumstances which, in the opinion of the investigator, would render the subject unfit for study inclusion.