Colonoscopy and Antiplatelet Therapy Trial

Exclusion Criteria

• •1. Coronary intervention (PCI or CABG) less than 90 days prior to randomization
• •2. ACS event in less than 90 days prior to randomization
• •3. Transient ischemic attack (TIA) and/or stroke event in less than 90 days prior to randomization
• •4. Acute limb ischemia and/or amputation in less than 90 days prior to randomization
• •5. Post cardiac valve replacement (either percutaneous or surgical)
• •6. High cardiovascular risk:
• •1. Patients with CCS class 4 angina
• •2. Hospitalized with ACS within 1 month prior to randomization
• •3. Patients undergoing PCI or CABG within the 3 months prior to randomization
• •7. Patients on left ventricular assist device (LVAD) or post cardiac transplantation
• •8. Patients with NYHA class 3 or 4 heart failure
• •9. Any condition requiring treatment requires chronic use of an anticoagulant.
• •10. Chronic kidney disease Stage 5 (with or without dialysis)
• •11. Liver cirrhosis with platelet count \< 50,000/ mm3 and/or INR \>1.4
• •12. Hematocrit \< 30% and hemoglobin \< 10 mg/dL
• •13. Emergent or inpatient Colonoscopy