Long-term Alterations of Host-microbiome Interactions and Cardiovascular and Respiratory Diseases Progression After Pneumonia

Inclusion Criteria

• •Group A (patients with acute cardiac disease)
• •Male or female
• •Age ≥ 40years old
• •Hospitalized for acute coronary syndrome for less than 7 days.
• •Informed consent from the patient
• •Person insured under a health insurance scheme
• •Group B (patients with chronic cardiovascular disease)
• •Male or female,
• •Age ≥ 40 years old
• •Undergoing coronary artery by-pass surgery
• •Hospitalized in intensive care unit for \> 12 hours
• •Informed consent from the patient
• •Person insured under a health insurance scheme
• •Group C (patients at risk of CVRD without chronic cardiovascular disease)
• •Male or female,
• •Age ≥ 40 years old
• •Familial high levels of cholesterol or triglycerides
• •With no personal history of CVRD, with a recent negative cardiac exercise test (last test inferior to 12 months)
• •Follow-up for lipid abnormalities at high risk of CVRD events
• •Informed consent from the patient
• •Person insured under a health insurance scheme
• •Group D (patients with HAP)
• •Male or female
• •Age ≥ 40years old
• •With one or more risk factors for CVD among:
• •smoking, abnormal lipidic levels, high blood pressure, obesity, diabetes mellitus, chronic kidney disease
• •Cured from mechanically ventilated HAP during the current hospitalization
• •Informed consent from the patient or relatives
• •Person insured under a health insurance scheme