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Long-term Alterations of Host-microbiome Interactions and Cardiovascular and Respiratory Diseases Progression After Pneumonia - the HOMI-LUNG Project - Hospital-Acquired-Pneumonia
The HOMI-LUNG - HAP study is part of the HOMI-LUNG project, funded by the Horizon Europe program. The "HOMI-LUNG" project is an international, interdisciplinary project that aims to better understand the causal links between respiratory tract infections (i.e. pneumonia) and the progression of cardiovascular disease. More specifically, the project aims to quantify the burden of cardiovascular disease after pneumonia and assess patients\' acceptability of long-term health alterations, as well as to define pneumonia endotypes with distinct pathobiological mechanisms associated with exacerbation of cardiovascular disease.
Age
40 - 80 years
Sex
ALL
Healthy Volunteers
No
Angers University Hospital
Angers, France
Nantes University Hospital
Nantes, France
Rennes University Hospital
Rennes, France
Rouen University Hospital
Rouen, France
Toulouse University Hospital
Toulouse, France
Start Date
January 2, 2025
Primary Completion Date
January 2, 2029
Completion Date
May 1, 2029
Last Updated
January 17, 2025
300
ESTIMATED participants
Blood samples
OTHER
Oropharyngeal swabs
OTHER
Calcium score (CT scan)
OTHER
ECG
OTHER
Cardiopulmonary exercise test, spirometry, plethysmography, pulmonary absorption of carbon monoxide in a single inspiration, and 6-minute walk test
OTHER
Lead Sponsor
Nantes University Hospital
Data Source & Attribution
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