Individualized Exploration of Aerobic Exercise-assisted Treatment of Depression

Exclusion Criteria

• •1. Diagnosed with other mental disorders, including schizophrenia, bipolar disorder, alcohol or substance abuse/dependence, eating disorders, etc.;
• •2. Individuals with intellectual disabilities or who are unable to cooperate for other reasons, or those lacking or having incomplete civil capacity during the onset of illness;
• •3. Suffering from neurological or organic brain diseases (such as stroke, cerebral hemorrhage, brain tumors, Parkinson's disease, epilepsy, etc.) and a history of severe traumatic brain injury;
• •4. Suffering from conditions with high exercise risk, such as hypertension or heart disease;
• •5. Currently undergoing systematic psychological therapy;
• •6. In the 3-minute step test, males with a recovery heart rate more than131 and females with a recovery heart rate more than 140;
• •7. Physically restricted individuals unable to participate in physical exercise;
• •8. Physical Activity Readiness Questionnaire (PAR-Q) score ≥ 2;
• •9. Pregnant women or individuals with contraindications to MRI examinations;
• •10. Individuals with severe suicidal tendencies or at risk of harming others.